3-Weeks South America Itinerary – 5 itineraries

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South America is such a massive continent and to be honest, 3-weeks here can be challenging. On the other hand, knowing what you want to do, see, and enjoy in South America will make your travel itinerary much easier to visualize and create.

3-weeks in South America if you are coming from Europe, North America, or Asia should be decided based on what you want to do. Remember, being in the southern hemisphere, the climate timeline is different here. For example, if you want to enjoy the stunning beaches of Brazil, you should come from December to April, if you want to go skiing, come visit from June to August.

In this guide about a 3-weeks South America itinerary, I will show you different options depending on the things you want to do and places you want to enjoy. From beach bumming to exploring the famous and so beautiful Andes Mountains.

ALSO READ: Smart packing for 3 weeks holiday trip


machu picchu, amazon river, glacier - 3 WEEKS SOUTH AMERICA ITINERARY (1)

Best time to go to South America

Before we dive in, let’s discuss a little bit about when to go to South America. As I mentioned before, you should know what you want to do here. Officially, summer starts in December and ends in March and winter starts in June and ends in September.

The best time to go to South America for summer is around November to avoid the big crowd and the heat or late March. If you don’t mind the crowd, definitely plan your trip around December to February.

The best time to visit South America for winter activities such as skiing is between July to August, but if you want to avoid that but still want to enjoy bearable winter, plan your trip around June or the end of September.

COVID restrictions in South America

Many countries in South America actually allow tourists to come in, especially vaccinated tourists. Although it’s not the easiest, I think we have to accept travelling will be like this for a while.

You will need to present your vaccination card or certificate. Some countries might have a website where you can upload this, which will give you a “permit to travel” in return, while others let the airline handle the paperwork.

You will also have to do a covid test (which has to be negative) 72 hours prior to arrival and another test upon arrival. Most countries in South America won’t require you to quarantine. However, in general, the wearing of a mask is mandated. Don’t forget to pack masks and hand sanitisers.

Here is a quick list of websites about COVID rules:

3-WEEKS SOUTH AMERICA (pinned map)

The pins are colour-coded to help you identify each itinerary or trail. To enlarge the map, click the top right corner icon. Credit: Map data: Google


Now to the fun part! I made four different itineraries for 3-weeks South America trip depending on the places and activities to be done. Check out which one you prefer below, I also added tips on visiting each place or country.

Every tourist, traveller, and holidaymaker is different. Some like to stay in one place for a longer time and explore as much as possible, Others don’t mind airports and like to see as many countries and cities as possible during their time off from work.

There are also people who want to really just relax during a vacation, sitting on the beach, reading a book, enjoying a cold drink. Some want to learn history, visit museums, and talk to the locals. Others are the ones who find the outdoor comforting, hiking and adventure are the key. And of course, the people who love to enjoy each country through its cousin.

I will try my best to accommodate all kinds of travellers, I hope you will find a thing or two to add to your 3-weeks South America itinerary.

Itinerary #1: Ecuador – Peru – Chile (Summer Trail)

If you want to escape the winter of the northern hemisphere and head down to South America, this beach trail for 3-week trip is perfect. As you can see, I’ve listed three countries, but it doesn’t mean you should visit all of them. You can either stay in one country and enjoy it or if you have the energy and curiosity, hope on planes because you are visiting major summer destinations in South America.

In my personal opinion, beaches in the west of South America are not as remarkable as the Caribbean or Brazil or Southeast Asia except for the Galapagos Islands. However, it has its own unique charm that will take your breath away. Plus there is less crowd here meaning you can enjoy your peace and quiet during your vacation. If you prefer to explore the Caribbean, here’s our Central America 3 weeks itinerary.


islets, ocean, corals, a small dome on top of a wall

As a country sitting right on top of the Andes Mountains, there are only a few places to go for some Vitamin Sea. Most tourists and locals head to the northwest part of Colombia. These beach spots are facing the stunning Caribbean Sea.

Barranquilla and Cartagena are the two most popular beach towns in Colombia. What I love the most about these places is how you get to enjoy the unbelievable beauty of the Caribbean without paying the Caribbean price. Compared to St. Lucia, Barbados, and Aruba – Barranquilla and Cartagena are much more affordable. Check out our 3 weeks in Colombia itinerary.

During your visit, the must-see places in Colombia for the summer holiday are Islas Del Rosario Catamaran for a snorkelling trip, La Boquilla and the Mangroves, Playa Blanca, Isla Grande, and Totumo mud volcano. Many of the islands can be reached through a booked boat tour. Make sure to enjoy a sunset Cartagena sunset cruise, and experience a bioluminescent plankton night tour.



If we are talking about beaches in Ecuador, one place that will come up to mind right away is Galapagos island. Which is not only popular for its stunning beaches but for its marine animals such as marine iguanas, tortoises, penguins, and sea lions.

Another beach area you should add to your list is Salinas. A great spot for the surfer and other wind, water sports. If you are landing at Olmeda International Airport which is in Guayaquil city, Salina is just an easy 144 kilometres (90 mi) hop.

If you want to avoid the crowd, just an hour north of Salina is Ayangue. It’s much quieter and more relaxing. Here, you can enjoy some small hiking trails, jump off the cliffs, or simply enjoy a book and a cold drink.

Other places you can visit for summer in Ecuador is Puerto Cayo, Mompiche, Muisine General Villamil, and Playa Los Frailes.



Peru has it all. The beauty of the Andes, great glacier lakes, bustling cities, old towns, and the cost. When I visited this country, I could literally come from a winter-like chill on the bones to it’s a hot day perfect for surfing on the same day. I flew from Cusco to Lima and experienced just that.

But, let’s talk about the beach for now. If you enjoy the wind and water sports combo, Lima has so much to offer you. You can visit Miraflores where you can head out and catch some wind by windsurfing or paragliding or swimming with the wild sea lions at Palomino Islands,. You can also simply take a nice walk along the beach or by the boardwalk if you don’t like sand on your feet. This area is very developed, you can find many restaurants to eat at, malls for shopping, and lots of little cafes by the shore.

If you prefer to be on your own and away from the crowd, head to Cabo Blanco, Los Organos, Huanchaco, and Las Pocitas. Where you can either go surfing or read a book at peace, these are the areas that are popular with the locals too.

Itinerary #2: Chile – Argentina (Winter Fun)

Some people, especially children, get their long vacation off from work during summer to match the school break. If you are looking for some winter fun during the summer in Europe or Northern America, check out this 3 weeks South America itinerary for winter.

Because of the precious Andes Mountains, the countries of Chile and Argentina are all perfect for all winter activities such as skiing and snowboarding. Ski resorts here are a bit cheaper than in North America or Europe but nonetheless, magnificent.



The most popular ski resort in Chile is called Valle Nevado which is just outside Santiago. Sitting in the heart of Nevado mountain, you know you will get the best winter in Chile here. You can enjoy skiing, snowboarding, and heli-skiing. If you are a beginner, don’t worry, you can get classes here as well. Valle Nevado also offers to lodge and hosts lots of events, but if you prefer to just stop by for one day visit, you can do that as well.

If you want less crowd, La Parva, literally next to Valle Nevado, is probably more suitable for you. It is sitting in the middle of three valleys giving you a handful of options of places to explore. They offer wide choices of winter activities, lodging, and other fun events to enjoy from young children to adults.

The best time to go skiing in Chile is from July until mid-September. I recommend it towards the end since the crowd will be slimmer or early July. You can also spend an entire 3 weeks in Chile.



Personally, I think Argentina is the best winter spot in South America. There are many options either you are looking for a fancy one, affordable, great for beginners, or the place for some challenging slopes.

Catedral Alta Patagonia is the most popular place for skiing, located near the border to Chile, southwest of Buenos Aires, it’s worth the travel though. With 1,480 acres of fine snow, there is so much you can do here. No wonder they also host international skiing competitions and host their own local competitions.

Apart from skiing, you can do snowboarding, bring your young children to the snow park, and play park. If you are a pro-skier or looking for some challenges, there are many spots that expert skiers are only allowed to use. You can definitely experiment and test your skills. They have accommodation, restaurants, and other activities, you can easily spend a week here.

If you don’t want to go too far from Buenos Aires, Las Lenas ski resort might be better for you. It’s also located near Santiago just right at the border. However, this is a smaller ski resort and more suitable for beginners. They offer classes and courses for beginners to different levels.

The ski season in Argentina is from mid-June until later October, but I recommend you go between July and September.

Itinerary #3: Peru – Bolivia – Chile (The Andes Mountains)


The Andes or Andean is definitely my favourite part of South America. It’s beautiful like no other, it’s massive, and it offers such diverse places to see. A large portion of South America sits on the top of the Andes, you can’t visit this continent and not explore a bit of it. In this part of the 3 weeks in South America itinerary, I will show you the places that you must not miss that feature the Andes region.

Both Peru and Chile are huge countries with so much to offer – from beaches, old cities, to mountains. I won’t even blame you if you decided to just stay put and explore in either country instead of hopping off to another country.


You can enjoy many activities here whenever you decide to come. For example, if you are looking for beach time, Lima offers surfing or a simple lay on the beach, book on hand. For hiking, there are literally dozens of mountains to climb and hundreds of hiking trails. And for a historical visit, well, Peru has so much to tell you. If you want to hike to Machu Picchu, keep in mind to check different options for Inca Trail Hike depending on your preference. We also have an extensive 3 weeks in Peru itinerary.

  • Day 1-7: Cusco; Spend 2 days acclimating yourself before heading to Machu Picchu, while in the city, you can enjoy some pico sour, traditional Peruvian meals such as ceviche, and visit many places and mountains around the city such as Rainbow Mountain, Maras (for salt mine exploration, quad biking). Remember that for visiting Machu Picchu, for short-trip, you can do a day trip, if you want to hike, you can choose between 2 days to 4 days. What I did was, I took a train, stayed for the night, hiked up to the citadel of Machu Picchu (where you can see the famous view), then hiked to the top of the mountain, finally, hiked down to the town and took the train next day back to Cusco.

  • Day 8-12: Arequipa; For history lovers, this part of Peru will blow your mind. Arequipa will show you Peru during the colonial era. It is also surrounded by 3 volcanoes, built with baroque-style buildings, and with a cherry on top 17th-century neoclassical Basilica Cathedral. Make sure to visit the historic centre of Plaza de Armas, Iglesia de la Compania, and get out of the city to visit Colca Canyon, Peru’s version of the Grand Canyon.
  • Day 13-15: Fly to Huascarán National Park (connect in Lima); If you want to see some pretty impressive glacier lakes of South America courtesy of the Andes Mountains, then get yourself to Huascarán National Park. It is over 400 kms (249 mi) north of Lima and while it has an airport, you will have to connect in Lima. Huascarán National Park has so many glacier lakes but the best is Lake 69, Laguna Cancaragá, and Laguna Paron.
  • Day 15-21: Lima; The capital of Peru also have a lot to offer. From its amazing beach where you can enjoy surfing and other water + wind sports combo, to fantastic outdoor activities such as repelling, canyoning, and sandboarding. Don’t forget to explore Malecon Miraflores, Barrancon, and Huaca Pucllana. Get yourself a ticket for a hop-on, hop-off bus which will make your city sightseeing much more convenient.


Chile’s most popular regions are Patagonia and Atacama desert. They are the opposite of each other, not only in location but also in things to offer. When you look at the map of Chile, you can easily say where the Atacama desert is, the entire north of Chile is part of this desert. Santiago, the capital is sitting at the border between these two regions.

REMEMBER: Direct flights to Chile are almost non-existing unless you are already in the region (coming from Argentina, Peru, etc). But if you are coming all the way from the US, Europe, or Asia, you might have to connect somewhere in between.

In a 3 weeks South America itinerary, you can cover both areas with plenty of time to enjoy both. I will start in the Atacama desert but if you want to start in the South, simply reverse the itinerary. Here is our recommended itinerary for 3 weeks in Chile only:

  • Day 1-5: Arrive at Aeropuerto Andrés Sabella (ANF) and base yourself in a small town called San Pedro de Atacama. Even though it’s a small area, there are plenty of accommodations to choose from. I recommend you spend the first day acclimatising your body until you are ready to explore. From here, you can visit Valle de la Luna, the smoking and active Geysers del Tatio, and Lagunas escondidas to cool off if you are feeling hot. It’s best if you book a tour to avoid some hassles. Don’t forget to visit the famous Los Flamencos National Reserve.
  • Day 6-9: Make your way to Santiago where you can explore the urban city and meets the old city. While Santiago is highly-developed with lots of high-rise buildings, exploring the area long enough, you will come across the undisturbed part of the city. Visit the tallest skyscraper in Santiago called Costanera Centre which also functions as a mall, especially a floor 61 & 62. Explore Museo de Arte Precolombino, and join a delicious wine tasting tour. From Santiago, you can also take a day trip to Valparaiso, Vina del Mar, and Casablanca Valley.
  • Day 10-15: Now, off to the Patagonia region. Head to Coyhaique, from here you can visit El Fraile if you want to ski, but this place is mostly for young children and beginners. About 100 kms is the magnificent Marble Cages located in Rio Ibanez. Don’t miss the Reserva Nacional Cerro Castillo for beautiful glacier lakes, hiking, and boating.
  • Day 16-21: The last bit of your trip, we have to make the most out of it. Make your way to Punta Arenas which is also known as the gateway to Antarctica. This is where tourists and researchers leave to head to Antarctica. From here, you can enjoy a magnificent area filled with penguins at Isla Magdalena. A little bit up north, from Puerto Natales, you can hop into a Patagonian Fjords tour and of course, visit Torres del Paine National Park.

All three

Now, for our airport lovers, you can visit all these three countries in 3 weeks, however, remember that you will have to choose just one place in each country. Personally, I don’t recommend this because the distance is too much and you will spend so much time at the airport, connecting flights, and buses.

If you really want to, the places I recommend you to combine are:

  • Peru, Bolivia, Chile
  • Brazil, Paraguay, Argentina
  • Peru, Chile, Argentina

Itinerary #4: Chile – Argentina – Uruguay (Southern Trail)


If you are eager to enjoy the Southern part of this continent and perhaps, reach the southernmost point, this 3 weeks in South America itinerary will be perfect for you. Perhaps, you are even thinking to get on a boat and exploring the stunning, Antarctica.

The only thing I want you to remember with this trail are:

For Chile, choose between the Atacama Desert and Patagonia. If you already visited Patagonian on the Chilean side, you can skip the Argentinian side and head to the north instead. Then in Uruguay, stick to the coast and don’t miss Montevideo, Playa Balconada, and Uruguay National Park.

Itinerary #5: Sao Paulo – Rio De Janeiro – Amazon River (Exploring Brazil)


Of course, I easily can’t justify 3 weeks in South America without talking about Brazil. It’s such a massive country that the only way I can recommend it is if you decide to spend the entire 20-day holiday here because there is just so much to see. From world-class beaches to the gateway of the Amazon river.

Brazil is such a huge country, the only for you to visit all these three major places is to take flights. Regardless, you can definitely spend 3 weeks in Brazil. I recommend you spend about one week in each place and then take a flight to the next. Remember that in the Amazon River, you will have to get on a tour for your safety and to make sure you have a fun time.

When visiting don’t miss out on seeing Christ the Redeemer in Rio, Copacabana Beach, Ipanema, and Sugarloaf Mountain. Rocinha Favela, Escadaria Selaron, and of course the annual Carnival Festival.

You can also head to Sao Paulo, not so far from Rio. In this city, you can visit the famous Museo de Futbol, and explore the areas of Santos, Sao Vicenta, and Guaruja. Make sure to book a city tour to make the most of your time there.


South America is a huge continent, and travelling here for 3 weeks is a challenge. It’s best to focus on just 1-2 countries and then come back for another time. It’s not like Europe where you can simply hop on an hour flight or a quick bus ride or train journey, the flights here take longer and are more expensive.

Instead of trying to visit more places, be present and enjoy each region, you will be exploring. I hope you found this 3-weeks South America itinerary helpful.


South America is too massive to spend only 3-weeks, this is why we made 5 different itineraries for you to choose from. via @threeweektraveller

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